Sexual Orientation & Gender Identity (SOGI)


Lesbian, Gay, Bisexual, Transgender, Queer, Intersex, Asexual/Aromantic and all sexually and gender diverse (LGBTQIA+) people are at a greater risk for mental health, cardiovascular, infectious, cancer, and other chronic illnesses due to historical discrimination and marginalization. Additionally, this community has historically been excluded from clinical research studies. As a result, there is a lack of the necessary information to study the effects of health treatments and interventions for the LGBTQIA+ population. The SOGI CRF aims to promote health equity by capturing this missing information.


  • The Sexual Orientation and Gender Identity (SOGI) CRF is optional.
    • Participants are able to opt-out of the form by simply answering, “No” to the first question, or by answering questions as “Unknown” or “Not reported.”
    • Date of Collection: Since this form may not be tied to a specific visit, this variable (SCDTC) is optional.
    • The form can be used by participants (i.e., subject-facing) during a visit with an ePRO device or any electronic data capture method.
  • The SOGI CRF provides additional demographic data for the Subject Characteristics (SC) domain and serves as an extension of the data collected using the Demographics (DM) domain.
  • New codelists have been created to capture Sex Assigned at Birth, Gender Identity, and Sexual Orientation.
    • The codelists and associated definitions are included in CDISC Controlled Terminology Package 58.
    • The SOGI team used the Fenway Health glossary to assist in the semantic development.
  • The Sex at Birth variable is different from the CDASH SEX variable.
    • Sex at Birth is as it was recorded on the participant's birth certificate by a medical professional (i.e. Sex Assigned at Birth).
    • This variable is not intended to be used with lab data (i.e.,  normal ranges).  

Sexual Orientation and Gender Identity
Sexual Orientation and Gender Identity
Was SOGI (Sexual Orientation and Gender Identity) data collected?Yes  No  
What [is/was] the date of the collection?
01 Jan 2000
What sex were you assigned at birth on your original birth certificate? (Check one):
Were you born with a variation in your physical sex characteristics? (this is sometimes called being intersex or having a difference in sex development)?
What is your gender identity at this time? (Check all that apply):
Which of the following represents how you think of your sexual orientation at this time? (Check all that apply):
* Mandatory field